HMSPCI complexes {apComplex} | R Documentation |
Affiliation matrices with rows corresponding to proteins and columns corresponding to complexes.
data(MBMEcHMSPCI) data(SBMHcHMSPCI) data(UnRBBcHMSPCI)
These are the results from an analysis of the HMS-PCI data (Ho et al., 2002) using the Protein Complex Membership Graph (PCMG) algorithm proposed by Scholtens and Gentleman (2004). These estimates were constructed using a sensitivity parameter of .75, specificity of .99, and external data based on Gene Ontology cellular component annotation.
MBMEcHMSPCI
contains multi-bait-multi-edge complex estimates. SBMHcHMSPCI
contains single-bait-multi-hit complex estimates. UnRBBcHMSPCI
contains unreciprocated bait-bait complex estimates.
Scholtens, D. and Gentleman, R. Making sense of high throughput protein-protein interaction data. (2004).
Ho, et al. Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry. Nature 415, 180-183 (2002).
data(MBMEcHMSPCI)