Package: vsn
Description: The package implements a robust variant of the
maximum-likelihood estimator for the stochastic model of
microarray data described in the references. The model
incorporates data calibration (aka normalization), a model for
the dependence of the variance on the mean intensity, and a
variance stabilizing data transformation. Differences between
transformed intensities are analogous to "normalized
log-ratios". However, in contrast to the latter, their
variance is independent of the mean, and they are usually more
sensitive and specific in detecting differential
transcription.
Version: 1.5.0
Author: Wolfgang Huber , contributions from A. von
Heydebreck , Markus Ruschhaupt
, D. Kostka
Maintainer: Wolfgang Huber
Dependencies: R (>= 1.8.0), Biobase (>= 1.4.14)
Suggests: affy, marray, multtest
SystemRequirements: None
License: LGPL
URL: http://www.r-project.org, http://www.dkfz.de/abt0840/whuber
Win32 package download